Purity : ≥98%
Molecular Weight : 545.62
Formula : C29H39NO9
General description
Homoharringtonine is a cephalotaxine alkaloid which inhibits the formation of diphenylalanine and acetylphenylalanyl-puromycin in liver ribosomes. Homoharringtonine has promising activity in hematologic malignancies and functions as an antileukemic. Homoharringtonine blocks the elongation phase of translation by binding to the 60-S ribosome subunit. Additionally, homoharringtonine has been shown to lower telomerase levels, inhibit protein synthesis, and induce apoptosis.
Storage condition
2-8°C in the dark
For Research Use Only. Not for use in diagnostic procedures.
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