3-异丁基-1-甲基黄嘌呤IBMX

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3-异丁基-1-甲基黄嘌呤IBMX

产品货号

产品名称

CAS号

包装

市场价（人民币）

库存状态

MG88935

3-异丁基-1-甲基黄嘌呤IBMX

28822-58-4

100mg

375.00

In stock

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产品概述
Molecular Weight : 222.24 Formula : C10H14N4O2 mp : 200-201 °C(lit.) Purity ≥99%(HPLC) Description Non-specific inhibitor of cAMP and cGMP phosphodiesterases. The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3 μM). Also serves as an adenosine receptor antagonist. Shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Induces calcium release from intracellular stores in sensory neurons. Solubility Soluble to 75 mM in DMSO and to 50 mM in ethanol. Storage Condition -20°C For Research Use Only. Not For Use In Diagnostic Procedures.

产品概述

Molecular Weight : 222.24

Formula : C10H14N4O2

mp : 200-201 °C(lit.)

Purity ≥99%(HPLC)

Description

Non-specific inhibitor of cAMP and cGMP phosphodiesterases. The increase in cAMP level as a result of phosphodiesterase inhibition by IBMX activates PKA leading to decreased proliferation, increased differentiation, and induction of apoptosis. IBMX inhibits phenylephrine-induced release of 5-hydroxytryptamine from neuroendocrine epithelial cells of the airway mucosa (IC50: 1.3 μM). Also serves as an adenosine receptor antagonist. Shown to inhibit ion channels in the neuromuscular junction, GH3 cells, and vascular smooth muscle cells. Induces calcium release from intracellular stores in sensory neurons.

Solubility
Soluble to 75 mM in DMSO and to 50 mM in ethanol.

Storage Condition

-20°C

For Research Use Only. Not For Use In Diagnostic Procedures.

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