钙黄绿素Calcein AM - 迈基生物

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钙黄绿素Calcein AM

产品货号

产品名称

CAS号

包装

市场价（人民币）

库存状态

MG1998

钙黄绿素Calcein AM

148504-34-1

1mg

1950.00

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产品概述
BioReagent, suitable for fluorescence Molecular Weight : 994.86 Molecular Formula : C46H46N2O23 λex 496 nm, λem 516 nm Purity ≥95% Application A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule. Description Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein, which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition. Storage condition -20°C and protect from light For Research Use Only. Not for use in diagnostic procedures.

产品概述

BioReagent, suitable for fluorescence

Molecular Weight : 994.86

Molecular Formula : C46H46N2O23

λex 496 nm, λem 516 nm
Purity ≥95%

Application
A non-fluorescent, membrane permeable probe that can be hydrolyzed to a fluorescent molecule.

Description

Calcein-AM is a hydrophobic non-fluorescent probe that can permeate the plasma membrane and can be hydrolyzed to Calcein, which is an extremely fluorescent and negatively charged molecule. The probe can be used to stain living cells and has been observed to fluoresce bright green in cytoplasmic Schwann cells. Calcein-AM has been reported to be a neutral substrate for Mdr (P-glycoprotein (Pgp) and multidrug resistance protein (MRP)) and has been used in flow cytometry studies to analyze the function of P-gp and MRP. Studies suggest that Calcein-AM can be used to detect MDR mediated resistance and to be transported by PGP from the plasma membrane. Mitochondrial permeability research has utilized Calcein as a cytosolic fluorophore. Has been used as a cytosolic fluorophore in mitochondrial permeability studies to image pore transition.

Storage condition
-20°C and protect from light

For Research Use Only. Not for use in diagnostic procedures.

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