Description
Xanthine is a purine base that can be found in most animal tissues and fluids. It is a product in the purine degradation pathway, produced by guanine deaminase from guanine, and by xanthine oxidoreductase from hypoxanthine. Xanthine is degraded to uric acid by xanthine oxidase. Clinically, xanthine and its derivatives act on sleep-inducing adenosine receptors as antagonists. Simple, direct and high-throughput assays for measuring xanthine find wide applications in research and drug discovery. MesGen Biotechnology xanthine assay kit uses a single Working Reagent that combines the xanthine oxidase reaction and color reaction in one step. The change in color intensity of the reaction product at 570 nm or fluorescence intensity at lex/em = 530/585 nm is directly proportional to xanthine concentration in the sample.

Application
Direct Assays: xanthine concentration in cell lysate, serum, and other biological samples.
Drug Discovery/Pharmacology: effects of drugs on xanthine (purine) metabolism.

Storage conditions
The kit is shipped on ice. Store all reagents at -20°C.

Shelf life
6 months after receipt.
 
产品仅供科学研究 禁止用于临床诊断、治疗
For Research Use Only. Not For Use In Diagnostic Procedures.