Molecular Weight : 323.13
Formula : C11H12Cl2N2O5
Biotechnology Grade , Purity (HPLC)(%)≥97.0
Description :
Chloramphenicol is a synthetic antibiotic, isolated from strains of Streptomyces venezuelae. It is often used for bacterial selection in molecular biology applications at 10-20 μg/mL and as a selection agent for transformed cells containing chloramphenicol reistance genes. Chloramphenicol inhibits bacterial protein synthesis by blocking the peptidyl transferase step by binding to the 50S ribosomal subunit and preventing attachment of aminoacyl tRNA to the ribosome. It also inhibits mitochondrial and chloroplast protein synthesis and ribosomal formation of (p)ppGpp, de-pressing rRNA transcription. This is a broad spectrum antibiotic against gram-positive and gram-negative bacteria, and is used mainly for ophthalmic and veterinary purposes.
Storge Condition :
Room Temperature. Stock solutions should be stored at 2-8°C and are stable at 37°C for 5 days.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.