3-Methyladenine (3-MA)
Cat # No. Product Name CAS Number Package List Price (CNY) Remarks
MG9192 3-Methyladenine (3-MA)
5142-23-450MG420In stock
5142-23-4100MG760In stock
5142-23-4500MG2750In stock
Product overview
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Molecular Weight : 149.15        Formula : C6H7N5
 
Description
3-Methyladenine (3-MA) is used to inhibit and study the mechanism of autophagy (lysosomal self-degradation) and apoptosis under various conditions. 3-MA inhibits autophagy by blocking autophagosome formation via the inhibition of type III Phosphatidylinositol 3-kinases (PI-3K). For use as an autophagy inhibitor, 3-MA is typically used at a concentration of 5 mM.
 
Preparation Note
This product is soluble in DMF (10 mg/ml, may require gentle heating), yielding a clear, colorless solution. It is also soluble in water, 95% ethanol, or 1 N NaOH at 30 mg/ml with heating, but upon cooling, the product precipitates from solution. Solutions of 3-MA are best prepared fresh.
 
 
Storage Condition
3 years    -20℃ powder
6 months-80℃ in solvent
 
For Research Use Only. Not For Use In Diagnostic Procedures. 
Product manual MSDS COA Reference